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The reaction of 1-bromobutane with sodium hydroxide affords the substitution product 1-butanol. What would happen to the rate of the reaction if the concentration of both 1-bromobutane and sodium hydroxide were doubled?


A) The rate remains the same.
B) The rate decreases by a factor of 2.
C) The rate increases by a factor of 2.
D) The rate increases by a factor of 4.

E) B) and D)
F) A) and B)

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Which of the following statements about an SN1 reaction mechanism is true?


A) The reaction is fastest with primary alkyl halide.
B) The reaction exhibits a one-step mechanism.
C) The reaction rate increases as the leaving group ability increases.
D) The reaction rate increases as the strength of the nucleophile increases.

E) A) and C)
F) B) and C)

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For the following reaction, use the identity of the alkyl halide and nucleophile to determine which substitution mechanism occurs. Then determine which solvent affords the faster reaction. For the following reaction, use the identity of the alkyl halide and nucleophile to determine which substitution mechanism occurs. Then determine which solvent affords the faster reaction.   A)  S<sub>N</sub>1, H<sub>2</sub>O B)  S<sub>N</sub>1, DMF C)  S<sub>N</sub>2, H<sub>2</sub>O D)  S<sub>N</sub>2, DMF


A) SN1, H2O
B) SN1, DMF
C) SN2, H2O
D) SN2, DMF

E) C) and D)
F) A) and C)

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Which of the following is a polar aprotic solvent? Which of the following is a polar aprotic solvent?   A)  I B)  II C)  III D)  IV


A) I
B) II
C) III
D) IV

E) B) and C)
F) All of the above

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