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Menopause:


A) is the cessation of menstrual cycles.
B) results in high plasma levels of estrogens.
C) occurs as a result of cessation of gonadotropin secretion.
D) is the cessation of ovulation while a baby is nursing.
E) is the pause in development of ovarian follicles occurring between the birth of a baby girl and when she reaches puberty.

F) A) and B)
G) A) and C)

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Which of the following hormones is NOT secreted by the placenta during pregnancy?


A) human placental lactogen
B) androgens
C) estradiol
D) progesterone
E) inhibin

F) A) and B)
G) A) and C)

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The secretory phase of the uterine cycle coincides with the follicular phase of the ovarian cycle.

A) True
B) False

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Lactation normally does not occur during pregnancy because


A) the breast ducts do not develop until after a baby is born.
B) the high levels of estrogen and progesterone in maternal plasma inhibit prolactin effects on the breasts.
C) maternal plasma levels of prolactin are low during pregnancy.
D) high levels of androgens inhibit milk synthesis by the breasts.
E) the low levels of circulating estrogen and progesterone during pregnancy inhibit milk synthesis by the breasts.

F) All of the above
G) D) and E)

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Which is a function of LH?


A) It stimulates androgen production by theca cells.
B) It stimulates the growth of granulosa cells.
C) It stimulates production of inhibin by theca cells.
D) It stimulates estrogen production by theca cells.
E) It inhibits GnRH secretion by the hypothalamus during ovulation.

F) B) and E)
G) A) and B)

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On day 14 of a typical 28 day menstrual cycle, LH concentration in the blood will be ________. The endometrium will be ________. Estrogen concentration in the blood is ________.


A) level; sloughing off; low
B) at or near a peak; near the end of the proliferative phase; relatively high
C) low but rising; in the secretory phase; high
D) at or near a peak; in the secretory phase; low
E) level; starting the proliferative phase; level but high

F) D) and E)
G) C) and E)

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Infertility treatments most often involve the injection of aromatases, leading to enhanced numbers of developing early ovarian antral follicles.

A) True
B) False

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Which of the following does progesterone INHIBIT during pregnancy?


A) the sensitivity of the myometrium to stimuli that promote contraction
B) plugging of the uterus by thickened cervical mucus
C) growth of the mammary glands
D) secretion of estrogen
E) regression of the corpus luteum

F) A) and E)
G) D) and E)

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Within the ovary, there are always a large number of ovarian follicles poised to release an ovum at ovulation.

A) True
B) False

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The onset of puberty is triggered by an increase in:


A) sensitivity of the gonads to pituitary gonadotropins.
B) sensitivity of the pituitary to GnRH.
C) GnRH secretion.
D) sensitivity of the hypothalamus to negative feedback by sex steroids.
E) sensitivity of the pituitary to negative feedback by sex steroids.

F) A) and B)
G) A) and C)

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The placenta is:


A) formed solely from the outermost layers of the embryonic trophoblast, and serves as an exchange organ between mother and fetus.
B) formed from interlocking fetal and maternal tissues, and allows the mother's blood to flow freely into the fetal circulation and back.
C) formed solely from the endometrial layer of the uterus, and allows the mother's blood to flow freely into the fetal circulation and back.
D) formed from interlocking fetal and maternal tissues, and serves as an exchange organ between mother and fetus.
E) formed from maternal circulatory stem cells, and serves as an exchange organ between mother and fetus.

F) C) and D)
G) B) and E)

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Which is TRUE during the luteal phase of the menstrual cycle?


A) Both estrogen and progesterone concentrations are kept low by negative feedback.
B) Estrogen concentration remains low, while progesterone concentration rises to a peak.
C) Progesterone concentration remains low, while estrogen concentration rises to a peak.
D) Progesterone concentration in the plasma is high, but estrogen concentration rises even higher.
E) Estrogen concentration in the plasma is high, but progesterone concentration rises even higher.

F) A) and D)
G) A) and C)

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Which of the following is NOT a function of estrogen during pregnancy?


A) stimulation of myometrial growth
B) maintenance of the endometrium
C) stimulation of prolactin secretion
D) stimulation of breast development
E) stimulation of milk synthesis

F) B) and E)
G) None of the above

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The female external genitalia are collectively called the vulva.

A) True
B) False

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The only cells of the testis that can secrete hormones are the Leydig cells.

A) True
B) False

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Amniocentesis is the removal of a sample of amniotic fluid for diagnosis of genetic or chromosomal disorders of the fetus.

A) True
B) False

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Beginning on the first day of the menstrual cycle, the order of phases in the uterus is:


A) proliferative, secretory, menstrual.
B) secretory, proliferative, menstrual.
C) menstrual, secretory, proliferative.
D) menstrual, proliferative, secretory.
E) secretory, menstrual, proliferative.

F) B) and E)
G) B) and D)

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The acrosome reaction is triggered by:


A) deposition of sperm into the female reproductive tract.
B) capacitation of sperm.
C) estrogen.
D) binding of the heads of sperm to the zona pellucida.
E) the first meiotic reduction division of the ovum.

F) None of the above
G) All of the above

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Which of the following does NOT normally produce androgens?


A) Leydig cells
B) theca cells
C) adrenal cortex cells
D) Sertoli cells

E) B) and C)
F) A) and B)

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One way in which gametogenesis in males differs from gametogenesis in females is that mitosis of primordial germ cells occurs in males only during fetal life.

A) True
B) False

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